Identification of AcrAB-TolC Efflux Pump Genes and Detection of Mutation in Efflux Repressor AcrR from Omeprazole Responsive Multidrug-Resistant Escherichia coli Isolates Causing Urinary Tract Infections
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منابع مشابه
Pimozide Inhibits the AcrAB-TolC Efflux Pump in Escherichia coli
Efflux pump inhibitors (EPIs) are attractive compounds to reverse multidrug-resistance in clinically relevant bacterial pathogens. In this study we tested the ability of the neuroleptic drug pimozide to inhibit the Escherichia coli AcrAB-TolC efflux pump, whose overproduction confers resistance to various antimicrobial agents. A real-time Nile red efflux assay in the AcrAB - overproducing strai...
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Abstract Background and Objectives: Efflux pumps are one of the main mechanisms for antibiotic resistance in Escherichia coli strains. The aim of this study was to investigate the relationship between 5 different efflux pump genes; acrA, acrB, emrA, emrB and mdtk and fluoroquinolone resistance in E.coli Isolated from patients with urinary tract infections in Qom. Methods: In this descriptive cr...
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ژورنال
عنوان ژورنال: Microbiology Insights
سال: 2019
ISSN: 1178-6361,1178-6361
DOI: 10.1177/1178636119889629